Migraine 'Caused by Genetic Defect'

Migraine 'Caused by Genetic Defect'

A very recent scientific study has found a genetic defect that could be linked to the cause of migraine headaches. The identification of this defect could point the way to better treatments for migraine patients across the globe.
The flawed gene was found in a family of migraine sufferers. This flawed gene is thought to be the cause of migraines, as the nature medicine study suggests.
This is a hugely important study and could be a massive step forward in understanding why up to one in five people suffer from debilitating migraine headaches.

The World Health Organization classifies migraine as being a leading cause of disability. Patients often experience crippling pain, usually on one side of the head, along with other neurological symptoms.
These other neurological symptoms, sometimes referred to as an 'aura' can include:

• Visual Disturbances (Scintillating Scotoma or Fortification Spectra)
• Aphasia (Problems Understanding Speech/Problems Communicating Through Language)
• Balance Problems
• Numbness Or Tingling Of A Limb
• Weakness Affecting One Side Of The Body

Migraine Gene

Until now, the genes that are directly responsible for causing migraine headaches have been unknown.
In this recent study, scientists have identified a gene known as TRESK. It is thought to be the direct cause of migraines in some patients.
The study states that if this gene is not working properly then environmental factors are more likely to trigger pain centres in the brain, leading to severe headaches.

This breakthrough means that scientists can now undergo the development of new drug treatments that could greatly benefit and may even cure some or most patients of their migraines completely.
A Dr. Aarno Palotie states, "It opens new avenues for planning new research which possibly could then lead to new treatments... but of course it's a long road."
A Dr. Cader, one of the leading researchers in the study also adds, "Previous studies have identified parts of our DNA that increase the risk in the general population, but have not found genes which can be directly responsible for common migraine.
"What we've found is that migraines seem to depend on how excitable our nerves are in specific parts of the brain.
"Finding the key player which controls this excitability will give us a real opportunity to find a new way to fight migraines and improve the quality of life for those suffering."